Anti-Aging Treatment

Prevention, Independence, and Self Care

Aging is a biological process involving many factors, such as cellular communication breakdown, loss of organ efficiency, systems miscommunications, and telomere shortening. This is heavily influenced by 2 key factors. The first is Epigenic, meaning how our behaviors and our environment influences our genes. Translation…lifestyle! The second is not typically in our control. This includes things such as our inherited genes, the lingering effects from chronic viral or bacterial infections, hidden exposures and even accidents and injuries.

At Upgrade medical we can influence many of these factors to help you to Feel Good, Look Good, and Live Good.

Core Anti-Aging Therapies and Solutions at Upgrade PDX

Senolytic Therapy in Portland, OR

Senolytic therapy, which is offered at our medical clinic in Portland, OR, is a concept and technique popular in the anti-aging community. The idea is to clear "zombie" cells that are stuck and not performing the role they are intended to do. Clearing these "zombie" cells offers a mechanism to reset the system. The number of senescent "zombie "cells in a person's body increases with age and has been linked to all chronic diseases. So, by clearing the body of these cells, we can potentially reduce disease burden and increase longevity. Although still a research-based model, there is extensive literature on the subject and several safe therapeutic options. This can be a powerful therapy when paired with other techniques such as healthy diet nutrient optimization, hormone replacement, peptides, and red light. Click to learn more.

What is Senolytic Therapy, and how does it benefit aging?

Senolytic therapy targets and clears senescent cells, often referred to as “zombie” cells. These cells no longer function properly but remain in the body, contributing to chronic inflammation and age-related diseases. By eliminating these cells, senolytic therapy can reduce disease burden, promote healthier aging, and potentially extend longevity. When combined with healthy lifestyle practices, nutrient optimization, and therapies like red light or peptide treatments, its effectiveness can be enhanced.

mTOR Pathway and Autophagy Induction

There are many options when it comes to anti-aging, and no definitive protocol has been agreed upon. There are however certain medications, peptides and herbs that cumulatively provide our current best options. Metformin RX and Rapamycin RX are 2 examples of repurposed prescriptions with good evidence. Both of these drugs are well researched and known to induce autophagy, the process whereby a cell cleans out and recycles debris. They target a specific pathway called mTOR. The inhibition of mTOR, triggers autophagy.
Metformin: Derived from an herb and synthesized into a medication for diabetes, metformin has been safely used for decades. It lowers blood glucose, reduces inflammation, and improves metabolomic parameters.
(Link: https://www.frontiersin.org/articles/10.3389/fendo.2021.718942/full)
Rapamycin: Originally discovered on Rapa Nui (Easter Island), it has been used for cancer, organ transplants, and as an antibiotic. It is considered the most promising anti-aging drug available.
(link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814615/)
Epithalon is a unique peptide that has been shown to lengthen telomeres on DNA. This function has a broad impact on multiple systems.
(link: Click to know more)

Evexipel and Hormone Replacement Therapy

It gets common to experience hormonal imbalance as we age. But with just a simple blood test, medical practitioners can figure it out. In any such case of imbalance, you may be recommended to undergo hormone optimization/hormone replacement therapy (HRT). Hormones are replaced through certain forms of medications, either orally or through patches and creams. Using EvexiPel Hormone Therapy can not just work on the hormonal imbalance but also help improve your overall health. We will examine you and determine the most suitable option.

The most common symptoms of hormonal imbalance are depression, mood swings, fatigue, sleep problems, anxiety, tension, loss of sex drive, night sweats, weight gain, memory loss, etc. This imbalance mostly affects the health of your bone, brain, breast, and heart.

NAD+ IV infusion therapy may provide many anti-aging benefits, such as:

Promoting healthier brain function
Slowing down cognitive decline
Reducing fatigue by improving cellular energy
Increasing metabolic efficiency
Decreasing inflammation, helping your body recover
Slowing the aging process by stimulating Sirtuins. Sirtuins regulate fat and glucose metabolism and play a role in inflammation, oxidative stress, and apoptosis, which helps regulate homeostasis, promoting longevity.

Peptide Therapy and Its Relationship to Anti-aging

At Upgrade PDX, we offer the "Fountain of Youth" peptide blend. This blend has been well-researched and includes 2 specific peptides, Epitalon and GHK. Epithalon (also known as Epitalon) and GHK-Cu are both peptides with promising therapeutic applications, especially in anti-aging, recovery, and overall cellular health. Epithalon is most researched for its ability to activate telomerase, an enzyme that protects and elongates telomeres. Telomeres are DNA sequences at the ends of chromosomes that shorten with age, and their preservation is linked to increased cellular lifespan. Studies on animal models and limited human trials suggest Epithalon may slow down the aging process and enhance longevity. GHK-Cu is known for its anti-inflammatory and regenerative properties, which support collagen production, enhance muscle recovery, and repair tissue. It also enhances blood flow to tissue.

Peptide therapy can be used in treating various health conditions. The hormone production managed by peptides takes control of numerous functions in your body, such as healing. Injecting peptides into the area to be treated increases the concentration of amino acids that help stimulate the healing of cells, generate muscles, and regenerate hair.

There are anti-aging properties in some of its supplements. This therapy can improve the functioning of your memory and skin quality. Thus, it helps in dealing with signs of aging like tightening and reducing frown lines, wrinkles, etc.

Epithalon: This peptide has been linked to anti-aging benefits by promoting better sleep, enhancing mood, and supporting overall longevity.

Copper Tripeptide

Mito Red Light Therapy

We use Mito Red Light Therapy to heal your skin, muscle tissue, and other parts of the body. The therapy involves exposing your skin to low levels of red or near-infrared lights using a lamp or laser device. The mitochondria soak up the light and make more energy when we do this. This process heals your skin manifold. Red light therapy is an effective and safe procedure.

Red Light Therapy

Click here to purchase a Biostrap device.

The human body ought to age, and when it ages, it also causes various illnesses, problems, and other discomforts. Some of the most common health conditions you may suffer while aging include chronic pain, dementia, difficulty walking or eating food, lack of energy, fatigue, etc.

You may schedule an appointment with us, and we ensure to offer the best lifestyle changes and treatment so that you age healthily.

Specialized Health and Wellness Treatments

• Chronic Disease Management

Chronic pain is one of the most common problems for people. Athletes, weekend warriors, and the elderly can all experience this issue. At Upgrade, we offer various approaches to treat your chronic pain, such as physical medicine, cryotherapy, standard and regenerative injections, IV therapy, and more. Depending upon the severity of your pain, we can combine these treatments with peptides, herbal and standard medication.

• Sexual Dysfunction Treatment

At Upgrade PDX, we have developed special approaches to address certain issues that cause people suffering.

Sexual dysfunction can be addressed via medications, peptide therapy, specific injections, and rehab services. It is a problem that is experienced by people of all ages. Both genders are prone to sexual dysfunction as they age. The doctor attends to each patient and provides them with precise treatment options, considering their unique concerns.

• Hair Restoration Treatment

Hair loss can be a problem that impacts your self-esteem and image. We have developed an approach that is effective by utilizing a combination of hormone therapy, specialty injections, medications, and peptides. After a complete checkup, the practitioner communicates the treatment methods that can help the patient restore the hair. It is important to commit to the process of treatment by following the instruction of the doctor. Multiple appointments are necessary for the complete procedure.

To know more, Refer the Document

• Cosmeceutical Peptides

Growth factors and cytokines have been used in the cosmetic products to help with aging skin, however, their large size limits their ability to penetrate the skin. Peptides provide benefits similar to growth factor with better skin penetration, due to their smaller molecular size. GHK and GHK-cu are considered excellent Botox-like peptides with pleotrophic effects.

• Hair Growth Peptides:

There are peptides to help with hair growth and stimulate new hair follicle production. The WNT pathway is a critical factor for hair growth and the discovery of the CXXC5 protein that is responsible for hair loss is a key target for therapy. Useful peptides include Thymulin, GHK-cu, and Thymosin Beta 4. These also pair well with both regenerative injections to the scalp and specialized prescription shampoos.

• Peptides for Sexual Health:

Sexuality and sexual health is an important part of the human condition. Dysfunction can lead to a host of both personal and relationship issues. Peptides offer a safe adjunctive treatment to address sexual dysfunction and libido alongside treatments such as hormone replacement and specialized regenerative injections. Particularly useful peptides include P41 and Melanotan II.

NAD+ IV therapy replenishes nicotinamide adenine dinucleotide (NAD+), a coenzyme critical for cellular energy production and metabolic efficiency. This therapy supports healthier brain function, reduces cognitive decline, boosts energy levels, and decreases inflammation. Additionally, NAD+ stimulates sirtuins, proteins that regulate aging processes such as oxidative stress and cell repair, making it a powerful tool in slowing the effects of aging.